Karen Appleton was born in Arlington va in 1956. She received her BFA from the Corcoran School of Art and her MFA from Virginia Commonwealth University in 1993. Appleton has exhibited her work throughout the Washington DC area, including The Gudelsky Gallery and The International Sculpture Center. Before pursuing her degrees, she studied painting with the late Leon  Berkowitz for many years.

She currently lives and works in Oakland California with her wife and their two children. Her work can be seen through Pro Arts online and is on view at Five Flavor Herbs in Oakland California.